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KMID : 0356920140670030164
Korean Journal of Anesthesiology
2014 Volume.67 No. 3 p.164 ~ p.170
Postoperative nausea and vomiting
Moon Young-Eun

Abstract
Postoperative nausea and vomiting (PONV) is a long-standing issue, not a new concept in anesthesiology. Despite many studies over the last several decades, PONV remains a significant problem due to its complex mechanism. This review presents a summary of the mechanism underlying the pathogenesis of PONV, focusing on preventive treatment, particularly the use of new drugs. In addition, we discuss the latest meta-analysis results regarding correct clinical use of classic drugs. I also summarize the latest trends of postdischarge nausea and vomiting and the pharmacogenetics, which is attracting a great deal of attention from other medical fields in PONV-related studies. Finally, we discuss the drawbacks of existing studies on PONV and suggest a focus for future investigations.
KEYWORD
Postdischarge nausea and vomiting, Postoperative nausea and vomiting, Prevention
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